A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea

Mandal, Debayan and Panda, Nilendu and Kumar, Shrabanti and Banerjee, Sukdeb and Mondal, Nirup B and Sahu, Niranjan P (2006) A Triterpenoid Saponin Possessing Antileishmanial Activity from the Leaves of Careya Arborea. Phytochemistry, 67 (2). pp. 183-190.

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    Abstract

    Bioguided-fractionation of the methanol extract of the leaves of Careya arborea led to isolation of a triterpenoid saponin, designated arborenin, and characterized as 3-O-b-D-glucopyranosyl(1!2)-b-D-glucopyranosyl-2a,3b-dihydroxy-taraxast-20-en-28-oic acid (1), together with desacylescin III (2). The structures were determined on the basis of extensive 2D NMR spectroscopic analysis. The saponin showed in vitro antileishmanial activity against Leishmania donovani (strain AG 83).

    Item Type: Article
    URI: http://www.eprints.iicb.res.in/id/eprint/1083
    Subjects: Chemistry
    Divisions: Indian Institute of Chemical Biology
    Depositing User: Mr Santanu Sadhukhan
    Date Deposited: 28 Dec 2011 16:00
    Last Modified: 03 Feb 2012 12:27
    Official URL: http://dx.doi.org/10.1016/j.phytochem.2005.10.028
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