Improved assay for genotyping haemophilia A carriers with intron 22 dinucleotide repeat marker

Saha, A and Mukherjee, S and Ray, Kunal (2006) Improved assay for genotyping haemophilia A carriers with intron 22 dinucleotide repeat marker. Haemophilia, 12 (2). pp. 200-201.

[img]

PDF
Restricted to IICB Scientists only

Download (125Kb) | Request a copy

    Abstract

    Haemophilia A, the most common bleeding disorder caused by defects in the Factor VIII gene (FVIII), affects one in 5000 males worldwide. Due to the inherent instability of the gene, caused by the presence of multiple copies of the same genomic regions, de novo mutation accounts for 40–50% of the gene defects. In addition, heterogeneous mutations have been detected covering its entire length

    Item Type: Article
    URI: http://www.eprints.iicb.res.in/id/eprint/464
    Subjects: Molecular & Human Genetics
    Divisions: Indian Institute of Chemical Biology
    Depositing User: Mr Shyamal Nath
    Date Deposited: 01 Nov 2011 17:35
    Last Modified: 07 Feb 2012 11:29
    Official URL: htpp://dx.doi.org/10.1111/j.1365-2516.2006.01205.x
    Links:

    Actions (login required)

    View Item