Indian Genetic Disease Database

Pradhan, Sanchari and Sengupta, Sengupta and Dutta, Anirban and Bhattacharyya, Kausik and Bag, Sumit K and Dutta, Chitra and Ray, Kunal (2011) Indian Genetic Disease Database. Nucleic Acids Research, 39. D933-D938.

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    Abstract

    Indians, representing about one-sixth of the world population, consist of several thousands of endogamous groups with strong potential for excess of populations depending on its structure, reproductive recessive diseases. However, no database is available on Indian population with comprehensive information the genetic disorders depend on identification of the on the diseases common in the country. Toaddress this issue, we present Indian Genetic Disease Database (IGDD) release 1.0 (http://www .igdd.iicb.res.in)—an integrated and curated repository of growing number of mutation data on common genetic diseases afflicting the Indian populations. Currently the database covers 52 diseases with information on 5760 individuals carrying the mutant alleles of causal genes. Information on locus heterogeneity, type of mutation, clinical and biochemical data, geographical location and common mutations are furnished based on published literature. The database is currently designed to work best with Internet Explorer 8 (optimal resolution 1440�900) and it can be searched based on disease of interest, causal gene, type of mutation and geographical location of the patients or carriers. Provisions have beenmade for deposition of new data and logistics for regular updation of the database. The IGDD web portal, planned to be made freely available, contains user-friendly interfaces and is expected to be highly useful to the geneticists, clinicians, biologists and patient support groups of various genetic diseases.

    Item Type: Article
    URI: http://www.eprints.iicb.res.in/id/eprint/54
    Subjects: Molecular & Human Genetics
    Structural Biology & Bioinformatics
    Divisions: Indian Institute of Chemical Biology
    Depositing User: Mr Shyamal Nath
    Date Deposited: 28 Sep 2011 19:41
    Last Modified: 27 Jan 2012 12:16
    Official URL: http://dx.doi.org/10.1093/nar/gkq1025
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