Purification and Characterization of Galactose-specific Lectin Receptors from Goat Epididymal Sperm Plasma Membrane and Their Role in Sperm Physiology

Das, Kaushik (2006) Purification and Characterization of Galactose-specific Lectin Receptors from Goat Epididymal Sperm Plasma Membrane and Their Role in Sperm Physiology. PhD thesis, Jadavpur University.

[img]

PDF
Restricted to IICB Scientists only until 01 January 2018.

Download (6Mb) | Request a copy

    Supervisors

    SupervisorsEmail
    Majumder, Gopal Chandra
    Dungdung, Sandhya Rekha

    Abstract

    The term lectin has its origin from latin word “legere” means to select or choose. Boyd was the pioneer to bring the lectin into describe a class of protein of plant origin which can agglutinate red blood cells according to their blood group (Boyd, 1954). Although early studies of lectin initiated by Stillmark in 1988 was within the plant source but subsequent discovery of haemaglutinins, agglutinins, phytohemagglutinins in diverse biological sources (e.g. bacteria, sponges, fungi, fishes, snails, eel and even animals) resulted in broadening the term lectin to include carbohydrate binding proteins (or glycoproteins) without regarding to their origin (Sharon, 1972; Goldstein et. al., 1980). Animal lectins are classified as C-lectins, which are Ca++ –dependent and are structurally related to the asialoglycoprotein receptor, and galectins, previously known as S-type lectins, which are thiol dependent and specifically bind β-galactoside residues (Drickamer & Taylor, 1993). C-type animal lectins are found in serum, extracellular matrix, and membranes

    Item Type: Thesis (PhD)
    URI: http://www.eprints.iicb.res.in/id/eprint/585
    Subjects: Cell Biology & Physiology
    Divisions: Indian Institute of Chemical Biology
    Depositing User: Mr Santanu Sadhukhan
    Date Deposited: 18 Nov 2011 14:19
    Last Modified: 18 Nov 2011 14:19
    Links:

    Actions (login required)

    View Item