Chemical Investigation on Bioactive Substances From Medicinal Plants

Pramanick, Swapan (2006) Chemical Investigation on Bioactive Substances From Medicinal Plants. PhD thesis, Jadavpur University.

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    Supervisors

    SupervisorsEmail
    Mukhopadhyay, Sibabrata

    Abstract

    Andrographis is a genus of Acanthaceae family, 21 species of which occur in India. The most useful one is Andrographis paniculata Nees.1,2 The herb A. paniculata is reported to possess tonic, astringent, anodyne and alexipharmic properties, and is helpful in dysentery, cholera, diabetes, consumption, influenza, bronchitis, swellings, itches, piles, and gonorrhoea.2 A decoction of the plant is reported to be a blood purifier and is used as a cure for torpid liver and jaundice. The leaves and roots are also used as febrifuge, tonic, stomachic, cholagogue and anthelmintic. A tincture of the root is tonic, stimulant and aperient.3 A compilation of the chemical constituents of the genus Andrographis, covering the literature upto 1997, has been done by Saxena et al.4 The present review is an attempt to compile and tabulate the chemical constituents of the genus Andrographis available in the literature till October, 2006. Their spectral data and biological activities not covered adequately earlier are also included. Semisynthetic studies leading to the preparation of a number of potent and novel analogues of andrographolide and interesting andrographolide metabolites have also been discussed.

    Item Type: Thesis (PhD)
    URI: http://www.eprints.iicb.res.in/id/eprint/649
    Subjects: Chemistry
    Divisions: Indian Institute of Chemical Biology
    Depositing User: Mr Santanu Sadhukhan
    Date Deposited: 24 Nov 2011 14:10
    Last Modified: 24 Nov 2011 14:10
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