Interaction of Annexin A6 with Alpha Actinin in Cardiomyocytes

Mishra, Sumita and Chander, Vivek and Banerjee, Priyam and Oh, Jae G and Lifirsu, Ekaterina and Park, Woo J and Kim, Do H and Bandyopadhyay, Arun (2011) Interaction of Annexin A6 with Alpha Actinin in Cardiomyocytes. BMC Cell Biology, 12 (7). pp. 2-8.

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    Abstract

    Annexins are calcium dependent phospholipid binding proteins that are expressed in a wide variety of tissues and implicated in various extra- and intracellular processes. In myocardial tissue, annexins A2, A5 and A6 are particularly abundant, of which the expression levels of annexin A6 has been found to be maximal. Conflicting reports from transgenic mice overexpressing annexin A6 or null mice lacking annexin A6 showed imbalances in intracellular calcium turnover and disturbed cardiac contractility. However, few studies have focussed on the signalling module of annexin A6 in the heart either in normal or in pathological state.

    Item Type: Article
    URI: http://www.eprints.iicb.res.in/id/eprint/70
    Subjects: Cell Biology & Physiology
    Divisions: Indian Institute of Chemical Biology
    Depositing User: Mr Shyamal Nath
    Date Deposited: 28 Sep 2011 19:38
    Last Modified: 06 Feb 2012 12:18
    Official URL: http://dx.doi.org/10.1186/1471-2121-12-7
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